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Diabetic / Metabolic Surgery

 

 

WHAT IS METABOLIC SYNDROME?

Metabolic syndrome is a disease that is manifested by weight gain, high blood glucose, hypertension, and high blood cholesterol. Metabolic Surgery is a procedure that is utilized to treat metabolic syndrome. The metabolic syndrome causes death due to organ failures, loss of function, critical physical losses, and cardiovascular diseases secondary to being overweight, being obese, type II diabetes, hypertension, high cholesterol, and gastrointestinal disorder.


%40 of people who have obesity are also diabetic and %80 of people who have type II diabetes are obese.

    It is considered that if a person meets at least 3 of the below criteria, they have metabolic syndrome.
  1. Waist circumference above 102 cm in men and above 88 cm in women
  2. Serum triglyceride 150 mg/dl or higher
  3. LDL cholesterol is lower than 40 mg/dl in men and lower than 50 mg/dl in women.
  4. Hypertension (>130/>85 mmHg)
  5. High blood glucose (>110 mg/dl)

In metabolic (diabetic) surgery, it is needed to be focused on the functional constraint. The only way to achieve this result is to activate the neuropeptide hormones that suppress appetite, originating from the ileum, in the early stages of nutrition. If the fullness signals sent by the intestines are too weak or late, the person eats too much until metabolic fullness might occur. With bariatric (weight loss surgery) and Metabolic surgery (diabetic surgery); obesity, hypertension, hyperlipidemia (high amount of lipid in the blood) and diabetes are taken under control and the foods are directly bypassed to the last segment of the small intestine. The foods are not surgically allowed to pass through the upper part of the small intestine and besides, secretion of certain hormones that cause insulin resistance will be inhibited.
With this method, the insulin that can be found in our body but cannot be utilized due to type II diabetes is made available again and either dose or number of insulin and antidiabetic agents, as well as antihypertensive and antihyperlipidemic drugs, is reduced.

WHICH SURGERIES ARE DONE WITH METABOLIC SURGERY?

Metabolic surgery procedures use a mechanism built on the principle of benefiting from hormonal changes through transposition/interposition procedures.
In metabolic surgery, beneficial effects include regulation of hormones and blood glucose that are independent of weight loss in type 2 diabetic patients with no severe weight problem. For this reason, there are two basic metabolic surgeries. First, one of these is Ileal Transposition (IT) and the second one is Transit Bipartition (TB) surgery.

Sleeve Gastrectomy

It is called Sleeve Stomach Surgery, as approximately 80% of the stomach is removed on the vertical plane, the capacity of the stomach is reduced to 20% and the feeling of hunger is suppressed

 

Advantages
  • A very safe procedure
  • A short-lasting procedure
  • Great success rate in treatment of obesity related diseases, especially diabetes, hypertension and hypercholesterolemia. Particularly, postoperative Year 1 cure rate is around 95 percent.
Complications
  • Leakage risk 0,4%
  • Bleeding risk 1,2%
  • Mortality risk 0,4%
  • Abscess risk 0,3%
  • Anemia risk 10%
  • Hernia risk 1%
Duration of Procedure 
  • 1-1.5 hours
Duration of Hospital Stay
  • 2-3 days

Laparoscopic Ileal Interposition

It is a procedure that involves connecting the upper part of the small intestine with the lower part. This surgery disrupts the hormones that cause insulin resistance and increases the level of hormones

 

Advantages
  • A very safe procedure
  • A short-lasting procedure
  • Great success rate in treatment of obesity related diseases, especially diabetes, hypertension and hypercholesterolemia. Particularly, postoperative Year 1 cure rate is around 95 percent.
Complications
  • Leakage risk 0,4%
  • Bleeding risk 1,2%
  • Mortality risk 0,4%
  • Abscess risk 0,3%
  • Anemia risk 10%
  • Hernia risk 1%
Duration of Procedure 
  • 1-1.5 hours
Duration of Hospital Stay
  • 2-3 days

Roux-en-Y Gastric Bypass RYGB

In Roux-en-Y Gastric Bypass surgery, the stomach size is reduced by creating a little pocket on the upper end and surgically stapling or taping it. Next, the smaller stomach is directly connected to the mid-segment of the small intestine (jejunum). In this way, the rest of the stomach and upper part of the intestine are bypassed (Duodenum). While it can be done with a large incision on the abdomen (open), it can also be done with a smaller incision and small equipment along with a camera (laparoscopy).

 

Advantages

  •  Most patients gradually lose weight without a certain diet or exercise
  •  This procedure doesn’t require implanting a foreign body
  • ·Since the gastrointestinal system is reconstructed, the patient will reduce calorie intake by eating less and feeling hungry less frequently.
  •  Fewer follow-up visits
  •  Weight loss reaches to %30 in three months and %60 in two years
Complications
  •     Leakage risk 1%
  •     Bleeding risk 2%
  •     Mortality risk 0,4%
  •     Abscess risk 1%
  •     Anemia risk 30%
  •     Hernia risk 3%
Duration of Procedure 
  • 2-2,5 hours
Duration of Hospital Stay
  • 3-5 days

Duodenojejunal Bypass Sleeve Gastrectomy

After a part of the stomach is removed with Sleeve Gastrectomy, the duodenum is connected to a point in the digestive system after a 2-meter segment of the small intestine is bypassed...

 

It is a new procedure for patients with BMI <30
Advantages
  • To prevent dumping syndrome by protecting the duodenum
  • Preventing remains of the stomach in order to eliminate the future risk of stomach cancer..
Complications
  •  
  • Leakage risk 1%
  • Bleeding risk 1%
  • Mortality risk 0,5%
  • Abscess risk 1%
  • Anemia risk 40%
  • Hernia risk 2%
Duration of Procedure 
  • 2-2,5 hours
Duration of Hospital Stay
  • 3-5 days

Mini Gastric Bypass

This is the modified version of classical Gastric Bypass which involves splitting the stomach vertically and closing with staplers to obtain a shape of the tube while the remaining stomach is left untouched and the new stomach is connected to 2-meter distal part of the intestine. In this surgery, foods moves from the new stomach to the small intestine, and a significant part of the intestine is bypassed and accordingly, absorption of foods decreases and moreover, amount of foods ingested will decrease to the small size of the new stoma

Advantages
  •          A very safe procedure
  •         A short-lasting procedure
  •         Weight loss results were comparable to classical Gastric Bypass surgery.
  •          It is considerably safer and easier than classical Gastric Bypass surgery and it lasts a shorter time. Since it involves less intestinal connections, the risk of complications is lower from a theoretical point of view.
  •          Great success is obtained in obesity-related diseases, especially diabetes, hypertension, and high cholesterol. Particularly, in type II diabetes, the postoperative year 1 cure rate is 95 percent.
Complications
  •          Leakage risk 0,1%
  •         Bleeding risk 1,2%
  •         Mortality risk 0,1%
  •         Abscess risk 0,3%
  •         Anemia risk 40%
  •         Hernia risk 1%
Duration of Procedure 
  • 1-1.5 hours
Duration of Hospital Stay
  • 2-3 days